Flotillin-1/Reggie-2 Protein Plays Dual Role in Activation of Receptor-tyrosine Kinase/Mitogen-activated Protein Kinase Signaling

Our previous work has shown that the membrane microdomain-associated flotillin proteins are potentially involved in epidermal growth factor (EGF) receptor signaling. Here we show that knockdown of flotillin-1/reggie-2 results in reduced EGF-induced phosphorylation of specific tyrosines in the EGF re...

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Main Authors: Amaddii, Monia, Meister, Melanie, Banning, Antje, Tomasovic, Ana, Mooz, Juliane, Rajalingam, Krishnaraj, Tikkanen, Ritva
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2012
主題:
Signal Transduction
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293549/
https://ncbi.nlm.nih.gov/pubmed/22232557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.287599
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