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Enhanced Bioavailability and Dissolution of Atorvastatin Calcium from Floating Microcapsules using Minimum Additives

Atorvastatin calcium, a lipid-lowering drug, is much less bioavailable because of reduced solubility in acidic media. Multiple-unit floating microcapsules of Atorvastatin calcium (ATC) were developed to expand the gastric residence time of the drug, as ATC has maximum rate of absorption in the upper...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Khan, Furquan Nazimuddin, Dehghan, Mohamed Hassan G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Österreichische Apotheker-Verlagsgesellschaft 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293352/
https://ncbi.nlm.nih.gov/pubmed/22396916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1104-26
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