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White-matter astrocytes, axonal energy metabolism, and axonal degeneration in multiple sclerosis

In patients with multiple sclerosis (MS), a diffuse axonal degeneration occurring throughout the white matter of the central nervous system causes progressive neurologic disability. The underlying mechanism is unclear. This review describes a number of pathways by which dysfunctional astrocytes in M...

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Detalhes bibliográficos
Main Authors: Cambron, Melissa, D'Haeseleer, Miguel, Laureys, Guy, Clinckers, Ralph, Debruyne, Jan, De Keyser, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293127/
https://ncbi.nlm.nih.gov/pubmed/22214904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.193
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