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High rates of de novo 15q11q13 inversions in human spermatozoa

Low-Copy Repeats predispose the 15q11-q13 region to non-allelic homologous recombination. We have already demonstrated that a significant percentage of Prader-Willi syndrome (PWS) fathers have an increased susceptibility to generate 15q11q13 deletions in spermatozoa, suggesting the participation of...

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Detalhes bibliográficos
Main Authors: Molina, Òscar, Anton, Ester, Vidal, Francesca, Blanco, Joan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293048/
https://ncbi.nlm.nih.gov/pubmed/22309495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8166-5-11
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