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Caveolae Are a Novel Pathway for Membrane-Type 1 Matrix Metalloproteinase Traffic in Human Endothelial Cells

The extracellular matrix (ECM) distinctly modulates membrane type 1-matrix metalloproteinase (MT1-MMP) in human endothelial cells (ECs). Herein, ECM-dependent RhoA activation is shown to regulate MT1-MMP localization and activity as well as clathrin-independent internalization in confluent ECs. In t...

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Bibliografiske detaljer
Main Authors: Gálvez, Beatriz G., Matías-Román, Salomón, Yáñez-Mó, María, Vicente-Manzanares, Miguel, Sánchez-Madrid, Francisco, Arroyo, Alicia G.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC329288/
https://ncbi.nlm.nih.gov/pubmed/14657245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-07-0516
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