A Genetic Risk Score is Associated with Incident Cardiovascular Disease and Coronary Artery Calcium - The Framingham Heart Study

BACKGROUND: Limited data exist regarding the use of a genetic risk score for predicting risk of incident cardiovascular disease (CVD) in US based samples. METHODS AND RESULTS: Using findings from recent GWAS, we constructed genetic risk scores (GRS) comprised of 13 genetic variants associated with m...

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Detalhes bibliográficos
Main Authors: Thanassoulis, George, Peloso, Gina M., Pencina, Michael J., Hoffmann, Udo, Fox, Caroline S., Cupples, L. Adrienne, Levy, Daniel, D'Agostino, Ralph B., Hwang, Shih-Jen, O'Donnell, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292865/
https://ncbi.nlm.nih.gov/pubmed/22235037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.111.961342
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