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Mechanism and Regulation of Nucleocytoplasmic Trafficking of Smad
Smad proteins are the intracellular mediators of transforming growth factor β (TGF-β) signaling. Smads function as transcription factors and their activities require carboxyl-terminal phosphorylation by TGF-β receptor kinases which are embedded in the cell membrane. Therefore, the translocation of a...
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3292837/ https://ncbi.nlm.nih.gov/pubmed/22204445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-1-40 |
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