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Mechanism and Regulation of Nucleocytoplasmic Trafficking of Smad

Smad proteins are the intracellular mediators of transforming growth factor β (TGF-β) signaling. Smads function as transcription factors and their activities require carboxyl-terminal phosphorylation by TGF-β receptor kinases which are embedded in the cell membrane. Therefore, the translocation of a...

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Detalhes bibliográficos
Main Authors: Chen, Xiaochu, Xu, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292837/
https://ncbi.nlm.nih.gov/pubmed/22204445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-1-40
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