Lysine methyltransferase G9a is not required for DNMT3A/3B anchoring to methylated nucleosomes and maintenance of DNA methylation in somatic cells

BACKGROUND: DNA methylation, histone modifications and nucleosome occupancy act in concert for regulation of gene expression patterns in mammalian cells. Recently, G9a, a H3K9 methyltransferase, has been shown to play a role in establishment of DNA methylation at embryonic gene targets in ES cells t...

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Bibliografiske detaljer
Main Authors: Sharma, Shikhar, Gerke, Daniel S, Han, Han F, Jeong, Shinwu, Stallcup, Michael R, Jones, Peter A, Liang, Gangning
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292817/
https://ncbi.nlm.nih.gov/pubmed/22284370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-5-3
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