Relationships of PBMC microRNA expression, plasma viral load, and CD4+ T-cell count in HIV-1-infected elite suppressors and viremic patients

BACKGROUND: HIV-1-infected elite controllers or suppressors (ES) maintain undetectable viral loads (< 50 copies/mL) without antiretroviral therapy. The mechanisms of suppression are incompletely understood. Modulation of HIV-1 replication by miRNAs has been reported, but the role of small RNAs in...

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Main Authors: Witwer, Kenneth W, Watson, Andria K, Blankson, Joel N, Clements, Janice E
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292811/
https://ncbi.nlm.nih.gov/pubmed/22240256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-5
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