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Semi-Automated Identification of N-Glycopeptides by Hydrophilic Interaction Chromatography, nano-Reverse-Phase LC-MS/MS, and Glycan Database Search

Glycoproteins fulfill many indispensable biological functions and changes in protein glycosylation have been observed in various diseases. Improved analytical methods are needed to allow a complete characterization of this complex and common posttranslational modification. In this study, we present...

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Main Authors: Pompach, Petr, Chandler, Kevin B., Lan, Renny, Edwards, Nathan, Goldman, Radoslav
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292689/
https://ncbi.nlm.nih.gov/pubmed/22239659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr201183w
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