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Validation of MRI Biomarkers of Hepatic Steatosis in the Presence of Iron Overload in the ob/ob Mouse

PURPOSE: To validate the utility and performance of a T(2)* correction method for hepatic fat quantification in an animal model of both steatosis and iron overload. MATERIALS AND METHODS: Mice with low (n=6), medium (n=6) and high (n=8) levels of steatosis were sedated and imaged using a chemical sh...

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Detalhes bibliográficos
Main Authors: Hines, Catherine D.G., Agni, Rashmi, Roen, Calista, Rowland, Ian, Hernando, Diego, Bultman, Eric, Horng, Debra, Yu, Huanzhou, Shimakawa, Ann, Brittain, Jean H., Reeder, Scott B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292661/
https://ncbi.nlm.nih.gov/pubmed/22127834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmri.22890
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