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Gelsolin Mediates Collagen Phagocytosis through a Rac-dependent Step

The role of gelsolin, a calcium-dependent actin-severing protein, in mediating collagen phagocytosis, is not defined. We examined α2β1 integrin-mediated phagocytosis in fibroblasts from wild-type (WT) and gelsolin knockout (Gsn(-)) mice. After initial contact with collagen beads, collagen binding an...

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Autors principals: Arora, Pamela D., Glogauer, Michael, Kapus, Andras, Kwiatkowski, David J., McCulloch, Christopher A.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC329256/
https://ncbi.nlm.nih.gov/pubmed/14617805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-07-0468
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