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Analysis of the Role of ZEB1 in the Pathogenesis of Posterior Polymorphous Corneal Dystrophy

PURPOSE. To determine how nonsense mutations in the transcription factor ZEB1 lead to the development of posterior polymorphous corneal dystrophy type 3 (PPCD3). METHODS. Whole-cell extracts were obtained from cultured human corneal epithelial cells (HCEpCs) as a source of ZEB1 protein. DNA-binding...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yellore, Vivek S., Rayner, Sylvia A., Nguyen, Catherine K., Gangalum, Rajendra K., Jing, Zhe, Bhat, Suraj P., Aldave, Anthony J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Association for Research in Vision and Ophthalmology, Inc. 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292363/
https://ncbi.nlm.nih.gov/pubmed/22199242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-8038
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