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Phosphoprotein phosphatase 2A: a novel druggable target for Alzheimer’s disease

Tau hyperphosphorylation is thought to play an important role in the etiology of Alzheimer’s disease by facilitating the formation of neurofibrillary tangles. Reducing phosphorylation through kinase inhibition has therefore emerged as a target for drug development, but despite considerable efforts t...

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Bibliografske podrobnosti
Main Authors: Voronkov, Michael, Braithwaite, Steven P, Stock, Jeffry B
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292348/
https://ncbi.nlm.nih.gov/pubmed/21644827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.11.47
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