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Phosphoprotein phosphatase 2A: a novel druggable target for Alzheimer’s disease

Tau hyperphosphorylation is thought to play an important role in the etiology of Alzheimer’s disease by facilitating the formation of neurofibrillary tangles. Reducing phosphorylation through kinase inhibition has therefore emerged as a target for drug development, but despite considerable efforts t...

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Detalhes bibliográficos
Main Authors: Voronkov, Michael, Braithwaite, Steven P, Stock, Jeffry B
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292348/
https://ncbi.nlm.nih.gov/pubmed/21644827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.11.47
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