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Phosphoprotein phosphatase 2A: a novel druggable target for Alzheimer’s disease
Tau hyperphosphorylation is thought to play an important role in the etiology of Alzheimer’s disease by facilitating the formation of neurofibrillary tangles. Reducing phosphorylation through kinase inhibition has therefore emerged as a target for drug development, but despite considerable efforts t...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3292348/ https://ncbi.nlm.nih.gov/pubmed/21644827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.11.47 |
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