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Non-additivity of sequence-specific enzyme-DNA interactions in the EcoRI DNA methyltransferase.

We describe a novel strategy to characterize protein-DNA interactions involving monomeric enzymes such as DNA methyltransferases (Mtases). This strategy is applied to our investigation of the EcoRI DNA Mtase, which binds its double stranded recognition site 5'-G-AATTC-3' and methylates the central a...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Reich, N O, Danzitz, M J
Format: Artigo
Language:Inglês
Published: Oxford University Press 1991
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329224/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1754395/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.23.6587
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