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Drug release from hydrazone-containing peptide amphiphiles

Hydrolytically-labile hydrazones in peptide amphiphiles were studied as degradable tethers for drug release from nanofiber gels. On-resin addition of the novel compound tri-Bochydrazido adipic acid to a lysine ε-amine allowed for precise placement of a hydrazide in a peptide sequence. Hydrazone form...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Matson, John B., Stupp, Samuel I.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292209/
https://ncbi.nlm.nih.gov/pubmed/21674107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1cc12570b
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