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Multivesicular Body Sorting: Ubiquitin Ligase Rsp5 Is Required for the Modification and Sorting of Carboxypeptidase S

The multivesicular body (MVB) sorting pathway provides a mechanism for delivering transmembrane proteins into the lumen of the lysosome/vacuole. Recent studies demonstrated that ubiquitin modification acts in cis as a signal for the sorting of cargoes into this pathway. Here, we present results from...

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Autors principals: Katzmann, David J., Sarkar, Srimonti, Chu, Tony, Audhya, Anjon, Emr, Scott D.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC329214/
https://ncbi.nlm.nih.gov/pubmed/14657247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-07-0473
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