Zuonin B Inhibits Lipopolysaccharide-Induced Inflammation via Downregulation of the ERK1/2 and JNK Pathways in RAW264.7 Macrophages

We investigated whether Zuonin B exerts immunological effects on RAW264.7 cells. Zuonin B, isolated from flower buds of Daphne genkwa, suppressed the levels of nitric oxide and prostaglandin E(2), as well as proinflammatory cytokines, such as tumor necrosis factor-α and interleukin-(IL-) 6, in lipop...

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Detalhes bibliográficos
Main Authors: Lee, Mee-Young, Yuk, Ji-Eun, Kwon, Ok-Kyung, Oh, Sei-Ryang, Lee, Hyeong-Kyu, Ahn, Kyung-Seop
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292044/
https://ncbi.nlm.nih.gov/pubmed/22454678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/728196
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