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Spontaneous deletions in Ig heavy chain genes: flanking sequences influence splice site selection.

The cell line G403.4.7, isolated as a spontaneous variant of the MPC-11 derived myeloma G403.4, produces a truncated gamma 2b HC protein, but no light chain (LC), and a single gamma 2b specific transcript of 2.4kb. This gamma 2b transcript consists of the VDJ and CH1 exons, the CH1 to Hinge (Hi) int...

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Dettagli Bibliografici
Autori principali: Ward, S B, Morrison, S L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1991
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC329201/
https://ncbi.nlm.nih.gov/pubmed/1754385
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