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TNF-α and TGF-β Counter-Regulate PD-L1 Expression on Monocytes in Systemic Lupus Erythematosus

Monocytes in patients with systemic lupus erythematosus (SLE) are hyperstimulatory for T lymphocytes. We previously found that the normal program for expression of a negative costimulatory molecule programmed death ligand-1 (PD-L1) is defective in SLE patients with active disease. Here, we investiga...

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Autors principals: Ou, Jing-Ni, Wiedeman, Alice E., Stevens, Anne M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291882/
https://ncbi.nlm.nih.gov/pubmed/22389764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00295
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