Prediction of phenprocoumon maintenance dose and phenprocoumon plasma concentration by genetic and non-genetic parameters

PURPOSE: The anticoagulation response to vitamin K antagonists is characterised by high inter-individual variability. The impact of single nucleotide polymorphisms (SNPs) in several genes of enzymes involved in the vitamin K cycle on phenprocoumon dose variability and phenprocoumon plasma concentrat...

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Main Authors: Geisen, Christof, Luxembourg, Beate, Watzka, Matthias, Toennes, Stefan W., Sittinger, Katja, Marinova, Milka, von Ahsen, Nicolas, Lindhoff-Last, Edelgard, Seifried, Erhard, Oldenburg, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
Assuntos:
Pharmacogenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291838/
https://ncbi.nlm.nih.gov/pubmed/21110013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00228-010-0950-y
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