Metabolomics of cerebrospinal fluid reveals changes in the central nervous system metabolism in a rat model of multiple sclerosis

Experimental Autoimmune Encephalomyelitis (EAE) is the most commonly used animal model for Multiple Sclerosis (MScl). CSF metabolomics in an acute EAE rat model was investigated using targetted LC–MS and GC–MS. Acute EAE in Lewis rats was induced by co-injection of Myelin Basic Protein with Complete...

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Main Authors: Noga, Marek J., Dane, Adrie, Shi, Shanna, Attali, Amos, van Aken, Hans, Suidgeest, Ernst, Tuinstra, Tinka, Muilwijk, Bas, Coulier, Leon, Luider, Theo, Reijmers, Theo H., Vreeken, Rob J., Hankemeier, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291832/
https://ncbi.nlm.nih.gov/pubmed/22448154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-011-0306-3
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