Low platelet counts after induction therapy for childhood acute lymphoblastic leukemia are strongly associated with poor early response to treatment as measured by minimal residual disease and are prognostic for treatment outcome

BACKGROUND: Numerous reports have been published on the association between kinetics of leukemic cells during early treatment of childhood acute lymphoblastic leukemia and therapeutic outcome. In contrast, little is known about the prognostic relevance of normal blood counts in this setting. DESIGN...

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Main Authors: Zeidler, Lutz, Zimmermann, Martin, Möricke, Anja, Meissner, Barbara, Bartels, Dorothee, Tschan, Christoph, Schrauder, André, Cario, Gunnar, Goudeva, Lilia, Jäger, Sarah, Ratei, Richard, Ludwig, Wolf-Dieter, Teigler-Schlegel, Andrea, Skokowa, Julia, Koehler, Rolf, Bartram, Claus R., Riehm, Hansjörg, Schrappe, Martin, Welte, Karl, Stanulla, Martin
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2012
Fag:
Original Articles and Brief Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291595/
https://ncbi.nlm.nih.gov/pubmed/22058224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.045229
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