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Low platelet counts after induction therapy for childhood acute lymphoblastic leukemia are strongly associated with poor early response to treatment as measured by minimal residual disease and are prognostic for treatment outcome

BACKGROUND: Numerous reports have been published on the association between kinetics of leukemic cells during early treatment of childhood acute lymphoblastic leukemia and therapeutic outcome. In contrast, little is known about the prognostic relevance of normal blood counts in this setting. DESIGN...

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Detalhes bibliográficos
Main Authors: Zeidler, Lutz, Zimmermann, Martin, Möricke, Anja, Meissner, Barbara, Bartels, Dorothee, Tschan, Christoph, Schrauder, André, Cario, Gunnar, Goudeva, Lilia, Jäger, Sarah, Ratei, Richard, Ludwig, Wolf-Dieter, Teigler-Schlegel, Andrea, Skokowa, Julia, Koehler, Rolf, Bartram, Claus R., Riehm, Hansjörg, Schrappe, Martin, Welte, Karl, Stanulla, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291595/
https://ncbi.nlm.nih.gov/pubmed/22058224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.045229
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