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How Cells Integrate Complex Stimuli: The Effect of Feedback from Phosphoinositides and Cell Shape on Cell Polarization and Motility

To regulate shape changes, motility and chemotaxis in eukaryotic cells, signal transduction pathways channel extracellular stimuli to the reorganization of the actin cytoskeleton. The complexity of such networks makes it difficult to understand the roles of individual components, let alone their int...

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Autori principali: Marée, Athanasius F. M., Grieneisen, Verônica A., Edelstein-Keshet, Leah
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291540/
https://ncbi.nlm.nih.gov/pubmed/22396633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002402
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