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A cell-based, high content screening assay reveals activators and inhibitors of cancer cell invasion
Acquisition of invasive cell behavior underlies tumor progression and metastasis. To define in more molecular detail the mechanisms underlying invasive behavior, we developed a high throughput screening strategy to quantitate invadopodia; actin-rich membrane protrusions of cancer cells which contrib...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3291516/ https://ncbi.nlm.nih.gov/pubmed/21791703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2002032 |
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