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Theoretical analysis of library screening using a N-dimensional pooling strategy.

A solution to the problem of library screening is analysed. We examine how to retrieve those clones that are positive for a single copy landmark from a whole library while performing only a minimum number of laboratory tests: the clones are arranged on a matrix (i.e in 2 dimensions) and pooled accor...

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Detalhes bibliográficos
Main Authors: Barillot, E, Lacroix, B, Cohen, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC329134/
https://ncbi.nlm.nih.gov/pubmed/1956784
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