Catenarin Prevents Type 1 Diabetes in Nonobese Diabetic Mice via Inhibition of Leukocyte Migration Involving the MEK6/p38 and MEK7/JNK Pathways

Inflammation contributes to leukocyte migration, termed insulitis, and β-cell loss in type 1 diabetes (T1D). Naturally occurring anthraquinones are claimed as anti-inflammatory compounds; however, their actions are not clear. This study aimed to investigate the effect and mechanism of catenarin on t...

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Autores principales: Shen, Ming-Yi, Lin, Yu-Ping, Yang, Bei-Chang, Jang, Yu-Song, Chiang, Chih-Kang, Mettling, Clément, Chen, Zeng-Weng, Sheu, Joen-Rong, Chang, Cicero L., Lin, Yea-Lih, Yang, Wen-Chin
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291164/
https://ncbi.nlm.nih.gov/pubmed/22454693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/982396
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