Hesperetin, a Selective Phosphodiesterase 4 Inhibitor, Effectively Suppresses Ovalbumin-Induced Airway Hyperresponsiveness without Influencing Xylazine/Ketamine-Induced Anesthesia

Hesperetin, a selective phosphodiesterase (PDE)4 inhibitor, is present in the traditional Chinese medicine, “Chen Pi.” Therefore, we were interested in investigating its effects on ovalbumin- (OVA-) induced airway hyperresponsiveness, and clarifying its rationale for ameliorating asthma and chronic...

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Detalhes bibliográficos
Main Authors: Shih, Chung-Hung, Lin, Ling-Hung, Hsu, Hsin-Te, Wang, Kuo-Hsien, Lai, Chi-Yin, Chen, Chien-Ming, Ko, Wun-Chang
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290907/
https://ncbi.nlm.nih.gov/pubmed/22454667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/472897
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