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Crosstalk between Smad and Mitogen-Activated Protein Kinases for the Regulation of Apoptosis in Cyclosporine A- Induced Renal Tubular Injury

BACKGROUND/AIMS: It remains elusive whether there is a crosstalk between Smad and mitogen-activated protein kinases (MAPKs) and whether it regulates cyclosporine A (CyA)-induced apoptosis in renal proximal tubular cells (RPTCs). METHODS: The effect of CyA on nuclear translocation of Smad2/3 and MAPK...

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Detalhes bibliográficos
Main Authors: Iwayama, Hideyuki, Sakamoto, Tatsuo, Nawa, Akihiro, Ueda, Norishi
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290860/
https://ncbi.nlm.nih.gov/pubmed/22470391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000333014
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