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Low Doses of Cadmium Chloride and Methallothionein-1-Bound Cadmium Display Different Accumulation Kinetics and Induce Different Genes in Cells of the Human Nephron

BACKGROUND/AIMS: The present study was conducted to investigate the renal tubular handling of inorganic cadmium (Cd(2+)) by exposing primary human tubular cell cultures to physiologically relevant doses of cadmium chloride (CdCl(2)). Furthermore, the cellular accumulation of Cd(2+) was compared to t...

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Detalhes bibliográficos
Main Authors: Cucu, Dana, D'Haese, Patrick C., De Beuf, Annelies, Verhulst, Anja
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290857/
https://ncbi.nlm.nih.gov/pubmed/22470376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000330069
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