The Role of Endoplasmic Reticulum Stress in Autoimmune-Mediated Beta-Cell Destruction in Type 1 Diabetes

Unlike type 2 diabetes which is caused by the loss of insulin sensitivity, type 1 diabetes (T1D) is manifested by the absolute deficiency of insulin secretion due to the loss of β mass by autoimmune response against β-cell self-antigens. Although significant advancement has been made in understandin...

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Bibliografiske detaljer
Main Authors: Zhong, Jixin, Rao, Xiaoquan, Xu, Jun-Fa, Yang, Ping, Wang, Cong-Yi
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Review Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290823/
https://ncbi.nlm.nih.gov/pubmed/22454627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/238980
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