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Hemodynamic, Vascular, and Reproductive Impact of FMS-Like Tyrosine Kinase 1 (FLT1) Blockade on the Uteroplacental Circulation During Normal Mouse Pregnancy

To investigate the role of FMS-like tyrosine kinase 1 (FLT1, also known as VEGFR1) signaling during pregnancy, mice were injected with anti-FLT1 neutralizing antibody (Ab) beginning on Gestational Day 8 or 12 and every other day thereafter until Day 18; vehicle-only injected mice served as controls....

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Detalhes bibliográficos
Main Authors: Khankin, Eliyahu V., Mandala, Maurizio, Colton, Ilsley, Karumanchi, S. Ananth, Osol, George
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290673/
https://ncbi.nlm.nih.gov/pubmed/22075472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.111.095380
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