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Actin binding to WH2 domains regulates nuclear import of the multifunctional actin regulator JMY
Junction-mediating and regulatory protein (JMY) is a regulator of both transcription and actin filament assembly. In response to DNA damage, JMY accumulates in the nucleus and promotes p53-dependent apoptosis. JMY's actin-regulatory activity relies on a cluster of three actin-binding Wiskott–Al...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Cell Biology
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3290644/ https://ncbi.nlm.nih.gov/pubmed/22262458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-12-0992 |
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