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The Mucin MUC4 and Its Membrane Partner ErbB2 Regulate Biological Properties of Human CAPAN-2 Pancreatic Cancer Cells via Different Signalling Pathways

The mucin MUC4 and its membrane partner the ErbB2 oncogenic receptor are potential interacting partners in human pancreatic tumour development. However, the way they function is still largely unknown. In this work, we aimed to identify the cellular mechanisms and the intracellular signalling pathway...

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Main Authors: Jonckheere, Nicolas, Skrypek, Nicolas, Merlin, Johann, Dessein, Anne Frédérique, Dumont, Patrick, Leteurtre, Emmanuelle, Harris, Ann, Desseyn, Jean-Luc, Susini, Christiane, Frénois, Frédéric, Van Seuningen, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290552/
https://ncbi.nlm.nih.gov/pubmed/22393391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032232
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