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A Genetic Variant in the Promoter Region of miR-106b-25 Cluster and Risk of HBV Infection and Hepatocellular Carcinoma

BACKGROUND: MiR-106b-25 cluster, hosted in intron 13 of MCM7, may play integral roles in diverse processes including immune response and tumorigenesis. A single nucleotide polymorphism (SNP), rs999885, is located in the promoter region of MCM7. METHODS: We performed a case-control study including 13...

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Autors principals: Liu, Yao, Zhang, Yixin, Wen, Juan, Liu, Li, Zhai, Xiangjun, Liu, Jibin, Pan, Shandong, Chen, Jianguo, Shen, Hongbing, Hu, Zhibin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290543/
https://ncbi.nlm.nih.gov/pubmed/22393390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032230
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