The cardiac renin-angiotensin system is responsible for high-salt diet-induced left ventricular hypertrophy in mice

AIMS: This study aimed to determine the role of the renin-angiotensin system (RAS) in high salt (HS) diet-induced left ventricular hypertrophy (LVH). METHODS AND RESULTS: Swiss mice were subjected to regular salt (RS) diet (0.6% NaCl), HS diet (4% NaCl) and HS plus irbesartan (50 mg/kg/day) or ramip...

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Main Authors: Le Corvoisier, Philippe, Adamy, Christophe, Sambin, Lucien, Crozatier, Bertrand, Berdeaux, Alain, Michel, Jean-Baptiste, Hittinger, Luc, Su, Jinbo
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290525/
https://ncbi.nlm.nih.gov/pubmed/20870672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurjhf/hfq146
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