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A Rapid, Reversible, and Tunable Method to Regulate Protein Function in Living Cells Using Synthetic Small Molecules

Rapid and reversible methods for perturbing the function of specific proteins are desirable tools for probing complex biological systems. We have developed a general technique to regulate the stability of specific proteins in mammalian cells using cell-permeable, synthetic molecules. We engineered m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Banaszynski, Laura A., Chen, Ling-chun, Maynard-Smith, Lystranne A., Lisa Ooi, A. G., Wandless, Thomas J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290523/
https://ncbi.nlm.nih.gov/pubmed/16959577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.07.025
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