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Estrogen regulation of the dopamine-activated GIRK channel in pituitary lactotrophs: implications for regulation of prolactin release during the estrous cycle

Prolactin (PRL), synthesized and secreted from lactotrophs of the anterior pituitary gland, is tonically inhibited by hypothalamic dopamine (DA) throughout the female reproductive (estrous) cycle. Our laboratory has shown that DA hyperpolarizes these cells by activating G protein-coupled inwardly re...

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Hlavní autoři: Christensen, Heather R., Zeng, Qinghua, Murawsky, Michael K., Gregerson, Karen A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290005/
https://ncbi.nlm.nih.gov/pubmed/21653876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00138.2011
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