Estrogen regulation of the dopamine-activated GIRK channel in pituitary lactotrophs: implications for regulation of prolactin release during the estrous cycle

Prolactin (PRL), synthesized and secreted from lactotrophs of the anterior pituitary gland, is tonically inhibited by hypothalamic dopamine (DA) throughout the female reproductive (estrous) cycle. Our laboratory has shown that DA hyperpolarizes these cells by activating G protein-coupled inwardly re...

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Bibliografiske detaljer
Main Authors: Christensen, Heather R., Zeng, Qinghua, Murawsky, Michael K., Gregerson, Karen A.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290005/
https://ncbi.nlm.nih.gov/pubmed/21653876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00138.2011
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