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Raltegravir in HIV-1 infection: Safety and Efficacy in Treatment-naïve Patients
The hunt for a compound which inhibits the HIV-1 integrase had been painstakingly difficult. Integrase is essential for viral replication as it mediates the integration of the viral DNA genome into the host DNA resulting in the establishment of the permanent provirus. Persistent efforts have resulte...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3289997/ https://ncbi.nlm.nih.gov/pubmed/22389581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CMRT.S5022 |
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