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2,2′-Dithiobis(5-nitropyridine) (DTNP) as an Effective and Gentle Deprotectant for Common Cysteine Protecting Groups

Of all the commercially-available amino acid derivatives for solid phase peptide synthesis, none has a greater abundance of sidechain protection diversity than cysteine. The high reactivity of the cysteine thiol necessitates its attenuation during peptide construction. Moreover, the propensity of cy...

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Détails bibliographiques
Auteurs principaux: Schroll, Alayne L., Hondal, Robert J., Flemer, Stevenson
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289972/
https://ncbi.nlm.nih.gov/pubmed/22083608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psc.1403
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