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Estimation of pairwise sequence similarity of mammalian enhancers with word neighbourhood counts

Motivation: The identity of cells and tissues is to a large degree governed by transcriptional regulation. A major part is accomplished by the combinatorial binding of transcription factors at regulatory sequences, such as enhancers. Even though binding of transcription factors is sequence-specific,...

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Main Authors: Göke, Jonathan, Schulz, Marcel H., Lasserre, Julia, Vingron, Martin
格式: Artigo
語言:Inglês
出版: Oxford University Press 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289921/
https://ncbi.nlm.nih.gov/pubmed/22247280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts028
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