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Structural, bioinformatic, and in vivo analyses of two Treponema pallidum lipoproteins reveal a unique TRAP transporter

Treponema pallidum, the bacterial agent of syphilis, is predicted to encode one tripartite ATP- independent periplasmic transporter (TRAP-T). TRAP-Ts typically employ a periplasmic substrate-binding protein (SBP) to deliver the cognate ligand to the transmembrane symporter. Herein, we demonstrate th...

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Main Authors: Deka, Ranjit K., Brautigam, Chad A., Goldberg, Martin, Schuck, Peter, Tomchick, Diana R., Norgard, Michael V.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289903/
https://ncbi.nlm.nih.gov/pubmed/22306465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.01.015
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