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Nanogel scavengers for drugs: Local anesthetic uptake by thermoresponsive nanogels

The use of functional nanogels based on poly(N-isopropylacrylamide) for effectively scavenging compounds (here, the model drug bupivacaine) is demonstrated using an in vitro cell-based assay. Nanogels containing higher loadings of acidic functional groups or more core-localized functional group dist...

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Detalhes bibliográficos
Main Authors: Hoare, Todd, Sivakumaran, Daryl, Stefanescu, Cristina, Lawlor, Michael W., Kohane, Daniel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289739/
https://ncbi.nlm.nih.gov/pubmed/22244983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2011.12.028
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