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Absence of RIP140 Reveals a Pathway Regulating glut4-Dependent Glucose Uptake in Oxidative Skeletal Muscle through UCP1-Mediated Activation of AMPK

Skeletal muscle constitutes the major site of glucose uptake leading to increased removal of glucose from the circulation in response to insulin. Type 2 diabetes and obesity are often associated with insulin resistance that can be counteracted by exercise or the use of drugs increasing the relative...

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Bibliographic Details
Main Authors: Fritah, Asmaà, Steel, Jennifer H., Parker, Nadeene, Nikolopoulou, Evanthia, Christian, Mark, Carling, David, Parker, Malcolm G.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289711/
https://ncbi.nlm.nih.gov/pubmed/22389706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032520
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