Development and Characterization of a Reverse Genetic System for Studying Dengue Virus Serotype 3 Strain Variation and Neutralization

Dengue viruses (DENV) are enveloped single-stranded positive-sense RNA viruses transmitted by Aedes spp. mosquitoes. There are four genetically distinct serotypes designated DENV-1 through DENV-4, each further subdivided into distinct genotypes. The dengue scientific community has long contended tha...

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Main Authors: Messer, William B., Yount, Boyd, Hacker, Kari E., Donaldson, Eric F., Huynh, Jeremy P., de Silva, Aravinda M., Baric, Ralph S.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289595/
https://ncbi.nlm.nih.gov/pubmed/22389731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001486
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