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A novel vascular clip design for the reliable induction of 2-kidney, 1-clip hypertension in the rat

The 2-kidney, 1-clip (2K1C) model has provided many insights into the pathogenesis of renovascular hypertension. However, studies using the 2K1C model often report low success rates of hypertension, with typical success rates of just 40–60%. We hypothesized that these low success rates are due to fu...

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Autors principals: Chelko, Stephen P., Schmiedt, Chad W., Lewis, Tristan H., Lewis, Stephen J., Robertson, Tom P.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289428/
https://ncbi.nlm.nih.gov/pubmed/22074718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01015.2011
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