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Palladium-Catalyzed Coupling of Functionalized Primary and Secondary Amines with Aryl and Heteroaryl Halides: Two Ligands Suffice in Most Cases

We report our studies on the use of two catalyst systems, based on the ligands BrettPhos (1) and RuPhos (2), which provide the widest scope for Pd-catalyzed C–N cross-coupling reactions to date. Often low catalyst loadings and short reaction times can be used with functionalized aryl and heteroaryl...

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Detalhes bibliográficos
Main Authors: Maiti, Debabrata, Fors, Brett P., Henderson, Jaclyn L., Nakamura, Yoshinori, Buchwald, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289414/
https://ncbi.nlm.nih.gov/pubmed/22384311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C0SC00330A
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