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Role of IFN-γ in the establishment of anterior chamber-associated immune deviation (ACAID)-induced CD8(+) T regulatory cells

Introduction of alloantigens into the AC induces a form of immune tolerance known as ACAID, which induces antigen-specific CD8(+) Tregs, contributing to ocular immune privilege by down-regulating immune responses. Recent evidence suggests IFN-γ is needed for the suppressive function of CD8(+) ACAID...

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Bibliografiske detaljer
Main Authors: Paunicka, Kathryn, Chen, Peter W., Niederkorn, Jerry Y.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Leukocyte Biology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289396/
https://ncbi.nlm.nih.gov/pubmed/22180630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0311173
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